In base hydrolysis of an amide, the nitrogen-containing product is which?

Master NCEA Level 3 Organic Chemistry Reaction Schemes. Prepare with multiple choice questions, complete with hints and detailed explanations. Ace your exam with our comprehensive tools!

Multiple Choice

In base hydrolysis of an amide, the nitrogen-containing product is which?

In base hydrolysis of an amide, the reaction splits the molecule into a carboxylate and the nitrogen-containing fragment as an amine. The hydroxide-driven mechanism cleaves the C–N bond, so the carbonyl portion becomes a carboxylate, while the nitrogen ends up as the amine (neutral, not protonated). This differs from acid hydrolysis, which gives a carboxylic acid and an ammonium salt form of the amine. Therefore, the nitrogen-containing product is an amine.

In base hydrolysis of an amide, the reaction splits the molecule into a carboxylate and the nitrogen-containing fragment as an amine. The hydroxide-driven mechanism cleaves the C–N bond, so the carbonyl portion becomes a carboxylate, while the nitrogen ends up as the amine (neutral, not protonated). This differs from acid hydrolysis, which gives a carboxylic acid and an ammonium salt form of the amine. Therefore, the nitrogen-containing product is an amine.

More practice questions